Fat transfer for breast augmentationPietro Gentile MD, Phd
Lipofilling and Lipostructure with adipose tissue graft with SVF and PRP: what is it?
The increasingly use of autologous adipose tissue added to SVF -Stromal Vascular Fraction Cells and/or to PRP Platelet Rich Plasma in soft tissue defections treatment, is the result of the growing demand for fat transfer breast augmentation.
The immediate gratification and the absence of prosthesis are the main reasons why patients require this kind of intervention. During the last five years, a growing number of scientific publications have described this subject. Stromal vascular fraction cells and adipose tissue fields of application are: outcomes of radiotherapy in breast cancer reconstruction, breast augmentation, outcomes of breast reconstruction after mastectomy, prosthesis removal outcomes. Nowadays, stromal vascular fraction can be obtained through minimal manipulation of adipose tissue, by using fat centrifugation procedures and mechanical filtration of it. SVF cell population contains adipose-derived stem cells called Adipose Derived Stem Cells (ASC).
ASC improve vascularization and adipose tissue survival by secreting various growth factors. In recent years we have published numerous scientific studies, after years of researches, regarding SVF, ASC and PRP mixed with adipose tissue for soft tissue defects reconstruction of the breasts (see scientific publication section).
The aim of the studies was to evaluate the fat engraftment in the breast through objective evaluation and long-term follow up. Preoperative and postoperative evaluation in our studies included complete clinical examination, photograph evaluation, nuclear magnetic resonance (NMR), breast ultrasound.
Press on PRP use in breast interventions.
I risultati degli interventi al seno con la chirurgia rigenerativa (…) risultano molto più naturali, creando un seno più morbido al tatto e nettamente più simile a quello vero.
Lipofilling and Lipostructure with adipose tissue graft with SVF and PRP: what are its limits?
The procedure is not suitable for every patient. First of all, it is necessary to carefully evaluate the tumor, its progression and the illness follow up in patients with breast cancer reconstruction outcomes.
Exclusion criteria have to be considered for this treatment. The exclusion criteria are divided into 2 categories: systemic and local. The systemic criteria include platelet disorders, thrombocytopenia, anti-aggregating therapy, bone marrow aplasia, uncompensated diabetes, sepsis, and cancer. The local criteria include cancer loss of substance.
In the case of breast hypoplasia, that is a less developed breast in terms of volume, it is necessary to careful evaluate during the medical examination whereas there are areas of the body with enough adipose tissue to be taken trough liposuction (abdomen, flank, thigh most commonly).
It is necessary to evaluate patient’s real needs and expectations, explaining him/her that there will be an adipose tissue resorption especially during the first six months. In some cases it is necessary to repeat the procedure as to achieve the adequate volume. The benefits will be a natural breast feeling to the touch and to the view.
Lipofilling and Lipostructure with adipose tissue graft with SVF and PRP: what outcomes could be supposed?
A higher fat engraftment percentage at breast level than traditional methods applied. Adipose tissue graft with SVF and PRP is a promising alternative to breast prosthesis. SVF and PRP, in fact, improve autologous adipose tissue viability.
Procedure explanation available in the video on the right.